Knockdown of ANGPTL4 May Reduce the Expression of LPL during Differentiation of 3T3-L1 Preadipocyte
نویسندگان
چکیده
Adipose tissue is a complex, highly metabolically active tissue. The expansion of adipose mainly affected by two processes: the number adipocytes and change adipocyte size. Adipocyte differentiation regulated multiple factors. 3T3-L1 preadipocyte line has become most widely studied cell for proliferation, regulation related genes. In our previous study, we found that ANGPTL4 was to through PPAR signaling pathway. Recent studies have shown functions regulating oncogenesis, vascular permeability, glucose homeostasis, lipid metabolism, energy homeostasis. this observed changes key genes expression before after inhibiting explore how influence on metabolism. Results shows that, LPL similar pattern. We suspect may form pathway, when suppressed it block pathway inhibit LPL.
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ژورنال
عنوان ژورنال: Austin journal of veterinary science & animal husbandry
سال: 2021
ISSN: ['2472-3371']
DOI: https://doi.org/10.26420/austinjvetscianimhusb.2021.1076